Metabolic Depletion of Atp by Fructose Inversely Controls Cd95- and Tumor Necrosis Factor Receptor 1–Mediated Hepatic Apoptosis

Hepatocyte apoptosis is crucial in several forms of liver disease. Here, we examined in different models of murine liver injury whether and how metabolically induced alterations of hepatocyte ATP levels control receptor-mediated apoptosis. ATP was depleted either in primary hepatocytes or in vivo by...

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Main Authors: Latta, Markus, Künstle, Gerald, Leist, Marcel, Wendel, Albrecht
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2000
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213521/
https://ncbi.nlm.nih.gov/pubmed/10839812
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