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Complexity in KSR function revealed by Raf inhibitor and KSR structure studies
The Ras, Raf, MEK and ERK proteins form an essential signal transduction pathway that is aberrantly activated in many human cancers. Kinase suppressor of Ras (KSR) is a conserved positive modulator of this pathway, and since its discovery, there has been a concerted effort to elucidate KSR function...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265819/ https://ncbi.nlm.nih.gov/pubmed/22292131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.5.17740 |
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