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Density of functional Ca(2+) release-activated Ca(2+) (CRAC) channels declines after T cell activation
CRAC channel-mediated Ca(2+) entry plays a crucial role in T lymphocyte activation. Activated T cells display enhanced Ca(2+) signaling compared with resting T cells; this is partially attributed to activation-induced upregulation of CRAC channel expression. Orai and Stim family genes encode CRAC ch...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265799/ https://ncbi.nlm.nih.gov/pubmed/22172731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.6.18222 |
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