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Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo

Entry of lymphocytes into secondary lymphoid organs (SLOs) involves intravascular arrest and intracellular calcium ion ([Ca(2+)](i)) elevation. TCR activation triggers increased [Ca(2+)](i) and can arrest T-cell motility in vitro. However the requirement for [Ca(2+)](i) elevation in arresting T cell...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Waite, Janelle C., Vardhana, Santosh, Shaw, Patrick J., Jang, Jung-Eun, McCarl, Christie-Ann, Cameron, Thomas O., Feske, Stefan, Dustin, Michael L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924891/
https://ncbi.nlm.nih.gov/pubmed/23939929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243255
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