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Bidirectional Coupling between Ryanodine Receptors and Ca(2+) Release-activated Ca(2+) (CRAC) Channel Machinery Sustains Store-operated Ca(2+) Entry in Human T Lymphocytes

The expression and functional significance of ryanodine receptors (RyR) were investigated in resting and activated primary human T cells. RyR1, RyR2, and RyR3 transcripts were detected in human T cells. RyR1/2 transcript levels increased, whereas those of RyR3 decreased after T cell activation. RyR1...

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Detalhes bibliográficos
Main Authors: Thakur, Pratima, Dadsetan, Sepehr, Fomina, Alla F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481322/
https://ncbi.nlm.nih.gov/pubmed/22948152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398974
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