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Whole-Cell Recording of Calcium Release-Activated Calcium (CRAC) Currents in Human T Lymphocytes

In T lymphocytes, depletion of Ca(2+) from the intracellular Ca(2+) store leads to activation of plasmalemmal Ca(2+) channels, called Calcium Release-Activated Calcium (CRAC) channels. CRAC channels play important role in regulation of T cell proliferation and gene expression. Abnormal CRAC channel...

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Detalhes bibliográficos
Main Authors: Thakur, Pratima, Fomina, Alla F.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159649/
https://ncbi.nlm.nih.gov/pubmed/21389932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2346
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