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Bidirectional Coupling between Ryanodine Receptors and Ca(2+) Release-activated Ca(2+) (CRAC) Channel Machinery Sustains Store-operated Ca(2+) Entry in Human T Lymphocytes
The expression and functional significance of ryanodine receptors (RyR) were investigated in resting and activated primary human T cells. RyR1, RyR2, and RyR3 transcripts were detected in human T cells. RyR1/2 transcript levels increased, whereas those of RyR3 decreased after T cell activation. RyR1...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481322/ https://ncbi.nlm.nih.gov/pubmed/22948152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398974 |
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