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Induction of TRPV1 desensitization by a biased receptor agonist

Selective suppression of hyperactive sensory neurons is an attractive strategy for managing pathological pain. Blocking Na(+) channels to eliminate action potentials and desensitizing transduction channels can both reduce sensory neuron excitability. The novel synthetic vanilloid ligand cap-ET prese...

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Detalhes bibliográficos
Main Authors: Wang, Elaine E, Li, Hui, Wang, Shu, Chuang, Alexander Y, Chuang, Huai-hu
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265794/
https://ncbi.nlm.nih.gov/pubmed/21829089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.6.17401
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