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Induction of TRPV1 desensitization by a biased receptor agonist
Selective suppression of hyperactive sensory neurons is an attractive strategy for managing pathological pain. Blocking Na(+) channels to eliminate action potentials and desensitizing transduction channels can both reduce sensory neuron excitability. The novel synthetic vanilloid ligand cap-ET prese...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265794/ https://ncbi.nlm.nih.gov/pubmed/21829089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.6.17401 |
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