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Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis

Sepsis-induced acute renal injury (AKI) occurs in 20%–50% of septic patients and nearly doubles the mortality rate of sepsis. Since treatment in the septic patient is usually only begun after the onset of symptoms, therapy that is effective even when delayed would have the greatest impact on patient...

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Autores principales: Wang, Zhen, Herzog, Christian, Kaushal, Gur P., Gokden, Neriman, Mayeux, Philip R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265793/
https://ncbi.nlm.nih.gov/pubmed/20577148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181ec39cc
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