Activation of Orexin 1 Receptors in the Periaqueductal Gray of Male Rats Leads to Antinociception via Retrograde Endocannabinoid (2-Arachidonoylglycerol)-Induced Disinhibition

Orexin A and B are hypothalamic peptides known to modulate arousal, feeding, and reward via OX(1) and OX(2) receptors. Orexins are also antinociceptive in the brain, but their mechanism(s) of action remain unclear. Here, we investigated the antinociceptive mechanism of orexin A in the rat ventrolate...

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Hlavní autoři: Ho, Yu-Cheng, Lee, Hsin-Jung, Tung, Li-Wei, Liao, Yan-Yu, Fu, Szu-Ying, Teng, Shu-Fang, Liao, Hsin-Tzu, Mackie, Ken, Chiou, Lih-Chu
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265563/
https://ncbi.nlm.nih.gov/pubmed/21994376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2671-11.2011
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