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Activation of Orexin 1 Receptors in the Periaqueductal Gray of Male Rats Leads to Antinociception via Retrograde Endocannabinoid (2-Arachidonoylglycerol)-Induced Disinhibition
Orexin A and B are hypothalamic peptides known to modulate arousal, feeding, and reward via OX(1) and OX(2) receptors. Orexins are also antinociceptive in the brain, but their mechanism(s) of action remain unclear. Here, we investigated the antinociceptive mechanism of orexin A in the rat ventrolate...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265563/ https://ncbi.nlm.nih.gov/pubmed/21994376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2671-11.2011 |
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