Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition

BACKGROUND AND PURPOSE: Capsaicin, an agonist of transient receptor potential vanilloid 1 (TRPV1) channels, is pro-nociceptive in the periphery but is anti-nociceptive when administered into the ventrolateral periaqueductal gray (vlPAG), a midbrain region for initiating descending pain inhibition. H...

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Bibliografski detalji
Glavni autori: Liao, H-T, Lee, H-J, Ho, Y-C, Chiou, L-C
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2011
Teme:
Research Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087135/
https://ncbi.nlm.nih.gov/pubmed/21232043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01214.x
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