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Expression of Neurog1 Instead of Atoh1 Can Partially Rescue Organ of Corti Cell Survival

In the mammalian inner ear neurosensory cell fate depends on three closely related transcription factors, Atoh1 for hair cells and Neurog1 and Neurod1 for neurons. We have previously shown that neuronal cell fate can be altered towards hair cell fate by eliminating Neurod1 mediated repression of Ato...

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Autors principals: Jahan, Israt, Pan, Ning, Kersigo, Jennifer, Calisto, Lilian E., Morris, Ken A., Kopecky, Benjamin, Duncan, Jeremy S., Beisel, Kirk W., Fritzsch, Bernd
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265522/
https://ncbi.nlm.nih.gov/pubmed/22292060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030853
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