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Neurog1 can partially substitute for Atoh1 function in hair cell differentiation and maintenance during organ of Corti development

Atoh1, a basic helix-loop-helix (bHLH) transcription factor (TF), is essential for the differentiation of hair cells (HCs), mechanotransducers that convert sound into auditory signals in the mammalian organ of Corti (OC). Previous work demonstrated that replacing mouse Atoh1 with the fly ortholog at...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Jahan, Israt, Pan, Ning, Kersigo, Jennifer, Fritzsch, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550966/
https://ncbi.nlm.nih.gov/pubmed/26209643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.123091
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