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Neurog1 can partially substitute for Atoh1 function in hair cell differentiation and maintenance during organ of Corti development

Atoh1, a basic helix-loop-helix (bHLH) transcription factor (TF), is essential for the differentiation of hair cells (HCs), mechanotransducers that convert sound into auditory signals in the mammalian organ of Corti (OC). Previous work demonstrated that replacing mouse Atoh1 with the fly ortholog at...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Jahan, Israt, Pan, Ning, Kersigo, Jennifer, Fritzsch, Bernd
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550966/
https://ncbi.nlm.nih.gov/pubmed/26209643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.123091
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