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Expression of Neurog1 Instead of Atoh1 Can Partially Rescue Organ of Corti Cell Survival

In the mammalian inner ear neurosensory cell fate depends on three closely related transcription factors, Atoh1 for hair cells and Neurog1 and Neurod1 for neurons. We have previously shown that neuronal cell fate can be altered towards hair cell fate by eliminating Neurod1 mediated repression of Ato...

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Detalhes bibliográficos
Main Authors: Jahan, Israt, Pan, Ning, Kersigo, Jennifer, Calisto, Lilian E., Morris, Ken A., Kopecky, Benjamin, Duncan, Jeremy S., Beisel, Kirk W., Fritzsch, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265522/
https://ncbi.nlm.nih.gov/pubmed/22292060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030853
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