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A novel pathway for human endothelial cell activation by antiphospholipid/anti-β(2) glycoprotein I antibodies

Antiphospholipid Abs (APLAs) are associated with thrombosis and recurrent fetal loss. These Abs are primarily directed against phospholipid-binding proteins, particularly β(2)GPI, and activate endothelial cells (ECs) in a β(2)GPI-dependent manner after binding of β(2)GPI to EC annexin A2. Because an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Allen, Kristi L., Fonseca, Fabio V., Betapudi, Venkaiah, Willard, Belinda, Zhang, Jainwei, McCrae, Keith R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265208/
https://ncbi.nlm.nih.gov/pubmed/22106343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-344671
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