Anti-β(2)GPI antibodies stimulate endothelial cell microparticle release via a nonmuscle myosin II motor protein-dependent pathway

The antiphospholipid syndrome is characterized by thrombosis and recurrent fetal loss in patients with antiphospholipid antibodies (APLAs). Most pathogenic APLAs are directed against β(2)-glycoprotein I (β(2)GPI), a plasma phospholipid binding protein. One mechanism by which circulating antiphosphol...

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Autori principali: Betapudi, Venkaiah, Lominadze, George, Hsi, Linda, Willard, Belinda, Wu, Meifang, McCrae, Keith R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843239/
https://ncbi.nlm.nih.gov/pubmed/23954892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-490318
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