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A novel pathway for human endothelial cell activation by antiphospholipid/anti-β(2) glycoprotein I antibodies
Antiphospholipid Abs (APLAs) are associated with thrombosis and recurrent fetal loss. These Abs are primarily directed against phospholipid-binding proteins, particularly β(2)GPI, and activate endothelial cells (ECs) in a β(2)GPI-dependent manner after binding of β(2)GPI to EC annexin A2. Because an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265208/ https://ncbi.nlm.nih.gov/pubmed/22106343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-344671 |
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