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Nab2 regulates secondary CD8(+) T-cell responses through control of TRAIL expression

CD4(+) Th cells are pivotal for the generation and maintenance of CD8(+) T-cell responses. “Helped” CD8(+) T cells receive signals during priming that prevent the induction of the proapoptotic molecule TNF-related apoptosis-inducing ligand (TRAIL) during reactivation, thereby enabling robust seconda...

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Detalhes bibliográficos
Main Authors: Wolkers, Monika C., Gerlach, Carmen, Arens, Ramon, Janssen, Edith M., Fitzgerald, Patrick, Schumacher, Ton N., Medema, Jan Paul, Green, Douglas R., Schoenberger, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265202/
https://ncbi.nlm.nih.gov/pubmed/22128144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-373910
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