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Interleukin-2 rescues helpless effector CD8(+) T cells by diminishing the susceptibility to TRAIL mediated death
CD8(+) T cells primed in the absence of CD4(+) T cell help are programmed to produce TRAIL, which results in Death receptor (DR5) mediated apoptosis upon restimulation. Here, we studied whether these `helpless' effector CD8(+) T cells are consigned to an apoptotic fate or whether their helpless...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146632/ https://ncbi.nlm.nih.gov/pubmed/21621553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2011.04.011 |
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