Integrating Cardiac PIP(3) and cAMP Signaling through a PKA Anchoring Function of p110γ

Adrenergic stimulation of the heart engages cAMP and phosphoinositide second messenger signaling cascades. Cardiac phosphoinositide 3-kinase p110γ participates in these processes by sustaining β-adrenergic receptor internalization through its catalytic function and by controlling phosphodiesterase 3...

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Main Authors: Perino, Alessia, Ghigo, Alessandra, Ferrero, Enrico, Morello, Fulvio, Santulli, Gaetano, Baillie, George S., Damilano, Federico, Dunlop, Allan J., Pawson, Catherine, Walser, Romy, Levi, Renzo, Altruda, Fiorella, Silengo, Lorenzo, Langeberg, Lorene K., Neubauer, Gitte, Heymans, Stephane, Lembo, Giuseppe, Wymann, Matthias P., Wetzker, Reinhard, Houslay, Miles D., Iaccarino, Guido, Scott, John D., Hirsch, Emilio
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265115/
https://ncbi.nlm.nih.gov/pubmed/21474070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.01.030
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