Integrating Cardiac PIP(3) and cAMP Signaling through a PKA Anchoring Function of p110γ

Adrenergic stimulation of the heart engages cAMP and phosphoinositide second messenger signaling cascades. Cardiac phosphoinositide 3-kinase p110γ participates in these processes by sustaining β-adrenergic receptor internalization through its catalytic function and by controlling phosphodiesterase 3...

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Hlavní autoři: Perino, Alessia, Ghigo, Alessandra, Ferrero, Enrico, Morello, Fulvio, Santulli, Gaetano, Baillie, George S., Damilano, Federico, Dunlop, Allan J., Pawson, Catherine, Walser, Romy, Levi, Renzo, Altruda, Fiorella, Silengo, Lorenzo, Langeberg, Lorene K., Neubauer, Gitte, Heymans, Stephane, Lembo, Giuseppe, Wymann, Matthias P., Wetzker, Reinhard, Houslay, Miles D., Iaccarino, Guido, Scott, John D., Hirsch, Emilio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265115/
https://ncbi.nlm.nih.gov/pubmed/21474070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.01.030
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