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Synthesis and Evaluation of a Fluorescent Ritterazine-Cephalostatin Hybrid

[Image: see text] The cephalostatin and ritterazine natural products comprise a potent family of bis-steroidal pyrazines that display potent single-digit nanomolar inhibition of tumor cell growth. An active fluorescent ritterazine-cephalostatin hybrid probe was developed using detailed SAR data deri...

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Detalhes bibliográficos
Main Authors: Kumar, Kanduluru Ananda, La Clair, James J., Fuchs, Philip L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264888/
https://ncbi.nlm.nih.gov/pubmed/21913733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol202139z
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