Loading...
Hot spot analysis for driving the development of hits into leads in fragment based drug discovery
Fragment based drug design (FBDD) starts with finding fragment-sized compounds that are highly ligand efficient and can serve as a core moiety for developing high affinity leads. Although the core-bound structure of a protein facilitates the construction of leads, effective design is far from straig...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264775/ https://ncbi.nlm.nih.gov/pubmed/22145575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci200468p |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|