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Determinants of the Specificity of Protease-activated Receptors 1 and 2 Signaling by Factor Xa and Thrombin

Factor Xa (FXa) elicits intracellular signaling responses through the activation of protease-activated receptor 2 (PAR2) and possibly also through PAR1 in endothelial cells. In this study, we investigated FXa signaling in endothelial cells when the protease was either in free form or assembled into...

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Detalhes bibliográficos
Main Authors: Rana, Soumendra, Yang, Likui, Hassanian, Seyed Mahdi, Rezaie, Alireza R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264766/
https://ncbi.nlm.nih.gov/pubmed/22034092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23427
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