The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

Lignende værker

• Contribution of Exosite Occupancy by Heparin to the Regulation of Coagulation Proteases by Antithrombin
  af: Yang, Likui, et al.
  Udgivet: (2009)
• Activation of protein C by the thrombin–thrombomodulin complex: Cooperative roles of Arg-35 of thrombin and Arg-67 of protein C
  af: Yang, Likui, et al.
  Udgivet: (2006)
• Protein Z-dependent Protease Inhibitor Binds to the C-terminal Domain of Protein Z
  af: Rezaie, Alireza R., et al.
  Udgivet: (2008)
• PAR-1 activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand
  af: Bae, Jong-Sup, et al.
  Udgivet: (2008)
• Identification of exosite residues of factor Xa involved in recognition of PAR-2 on endothelial cells
  af: Manithody, Chandrashekhara, et al.
  Udgivet: (2012)