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Effects of BRCA2 deficiency on telomere recombination in non-ALT and ALT cells

BACKGROUND: Recent studies suggest that BRCA2 affects telomere maintenance. Interestingly, anti cancer treatments that involve BRCA2 and telomerase individually are currently being explored. In the light of the above recent studies their combinatorial targeting may be justified in the development of...

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Autors principals: Sapir, Ester, Gozaly-Chianea, Yaghoub, Al-Wahiby, Suliman, Ravindran, Sainu, Yasaei, Hemad, Slijepcevic, Predrag
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264516/
https://ncbi.nlm.nih.gov/pubmed/22152194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-2-9
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