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Genetic Informational RNA Is Not Required for Recombinant Prion Infectivity

Whether a genetic informational nucleic acid is required for the infectivity of transmissible spongiform encephalopathies is central to the debate about the infectious agent. Here we report that an infectious prion formed with bacterially expressed recombinant prion protein plus synthetic polyriboad...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Fei, Zhang, Zhihong, Wang, Xinhe, Li, Jiali, Zha, Liang, Yuan, Chong-Gang, Weissmann, Charles, Ma, Jiyan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264365/
https://ncbi.nlm.nih.gov/pubmed/22090130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06216-11
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