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Genetic Informational RNA Is Not Required for Recombinant Prion Infectivity

Whether a genetic informational nucleic acid is required for the infectivity of transmissible spongiform encephalopathies is central to the debate about the infectious agent. Here we report that an infectious prion formed with bacterially expressed recombinant prion protein plus synthetic polyriboad...

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Detalhes bibliográficos
Main Authors: Wang, Fei, Zhang, Zhihong, Wang, Xinhe, Li, Jiali, Zha, Liang, Yuan, Chong-Gang, Weissmann, Charles, Ma, Jiyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264365/
https://ncbi.nlm.nih.gov/pubmed/22090130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06216-11
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