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De novo generation of infectious prions with bacterially expressed recombinant prion protein
The prion hypothesis is strongly supported by the fact that prion infectivity and the pathogenic conformer of prion protein (PrP) are simultaneously propagated in vitro by the serial protein misfolding cyclic amplification (sPMCA). However, due to sPMCA's enormous amplification power, whether a...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Federation of American Societies for Experimental Biology
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834773/ https://ncbi.nlm.nih.gov/pubmed/23970796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-233965 |
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