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De novo generation of infectious prions with bacterially expressed recombinant prion protein
The prion hypothesis is strongly supported by the fact that prion infectivity and the pathogenic conformer of prion protein (PrP) are simultaneously propagated in vitro by the serial protein misfolding cyclic amplification (sPMCA). However, due to sPMCA's enormous amplification power, whether a...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Federation of American Societies for Experimental Biology
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834773/ https://ncbi.nlm.nih.gov/pubmed/23970796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-233965 |
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