De novo generation of infectious prions with bacterially expressed recombinant prion protein

The prion hypothesis is strongly supported by the fact that prion infectivity and the pathogenic conformer of prion protein (PrP) are simultaneously propagated in vitro by the serial protein misfolding cyclic amplification (sPMCA). However, due to sPMCA's enormous amplification power, whether a...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Zhihong, Zhang, Yi, Wang, Fei, Wang, Xinhe, Xu, Yuanyuan, Yang, Huaiyi, Yu, Guohua, Yuan, Chonggang, Ma, Jiyan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2013
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834773/
https://ncbi.nlm.nih.gov/pubmed/23970796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-233965
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