Decoding the Functional Roles of Cationic Side Chains of the Major Antimicrobial Region of Human Cathelicidin LL-37

Human cathelicidin LL-37 is a critical cationic antimicrobial peptide for host defense against infection, immune modulation, and wound healing. This article elucidates the functional roles of the cationic side chains of the major antimicrobial region of LL-37, corresponding to residues 17 to 32 (des...

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Main Authors: Wang, Guangshun, Epand, Raquel F., Mishra, Biswajit, Lushnikova, Tamara, Thomas, Vinai Chittezham, Bayles, Kenneth W., Epand, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Mechanisms of Action: Physiological Effects
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264245/
https://ncbi.nlm.nih.gov/pubmed/22083479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05637-11
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