Decoding the Functional Roles of Cationic Side Chains of the Major Antimicrobial Region of Human Cathelicidin LL-37

Human cathelicidin LL-37 is a critical cationic antimicrobial peptide for host defense against infection, immune modulation, and wound healing. This article elucidates the functional roles of the cationic side chains of the major antimicrobial region of LL-37, corresponding to residues 17 to 32 (des...

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Autores principales: Wang, Guangshun, Epand, Raquel F., Mishra, Biswajit, Lushnikova, Tamara, Thomas, Vinai Chittezham, Bayles, Kenneth W., Epand, Richard M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264245/
https://ncbi.nlm.nih.gov/pubmed/22083479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05637-11
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