Transformation of Human Cathelicidin LL-37 into Selective, Stable, and Potent Antimicrobial Compounds

[Image: see text] This Letter reports a family of novel antimicrobial compounds obtained by combining peptide library screening with structure-based design. Library screening led to the identification of a human LL-37 peptide resistant to chymotrypsin. This d-amino-acid-containing peptide template w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Guangshun, Hanke, Mark L., Mishra, Biswajit, Lushnikova, Tamara, Heim, Cortney E., Chittezham Thomas, Vinai, Bayles, Kenneth W., Kielian, Tammy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2014
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168778/
https://ncbi.nlm.nih.gov/pubmed/25061850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500475y
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg