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Lipid Segregation Explains Selective Toxicity of a Series of Fragments Derived from the Human Cathelicidin LL-37

The only human cathelicidin, the 37-residue peptide LL-37, exhibits antimicrobial activity against both gram-positive and gram-negative bacteria. We studied the ability of several fragments of LL-37, exhibiting different antimicrobial activities, to interact with membranes whose compositions mimic t...

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Detalhes bibliográficos
Main Authors: Epand, Raquel F., Wang, Guangshun, Berno, Bob, Epand, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737875/
https://ncbi.nlm.nih.gov/pubmed/19581460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00321-09
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