Global Analysis of the Staphylococcus aureus Response to Mupirocin

In the present study, we analyzed the response of S. aureus to mupirocin, the drug of choice for nasal decolonization. Mupirocin selectively inhibits the bacterial isoleucyl-tRNA synthetase (IleRS), leading to the accumulation of uncharged isoleucyl-tRNA and eventually the synthesis of (p)ppGpp. The...

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書誌詳細
主要な著者: Reiß, Swantje, Pané-Farré, Jan, Fuchs, Stephan, François, Patrice, Liebeke, Manuel, Schrenzel, Jacques, Lindequist, Ulrike, Lalk, Michael, Wolz, Christiane, Hecker, Michael, Engelmann, Susanne
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
主題:
Mechanisms of Action: Physiological Effects
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264241/
https://ncbi.nlm.nih.gov/pubmed/22106209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05363-11
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