Global Analysis of the Staphylococcus aureus Response to Mupirocin

In the present study, we analyzed the response of S. aureus to mupirocin, the drug of choice for nasal decolonization. Mupirocin selectively inhibits the bacterial isoleucyl-tRNA synthetase (IleRS), leading to the accumulation of uncharged isoleucyl-tRNA and eventually the synthesis of (p)ppGpp. The...

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Detaylı Bibliyografya
Asıl Yazarlar: Reiß, Swantje, Pané-Farré, Jan, Fuchs, Stephan, François, Patrice, Liebeke, Manuel, Schrenzel, Jacques, Lindequist, Ulrike, Lalk, Michael, Wolz, Christiane, Hecker, Michael, Engelmann, Susanne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Mechanisms of Action: Physiological Effects
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264241/
https://ncbi.nlm.nih.gov/pubmed/22106209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05363-11
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