Anidulafungin for Neonatal Hematogenous Candida Meningoencephalitis: Identification of Candidate Regimens for Humans Using a Translational Pharmacological Approach

Hematogenous Candida meningoencephalitis (HCME) is a serious infection in premature neonates. Anidulafungin is an echinocandin antifungal agent with potent activity against Candida spp., but its efficacy and optimal regimens for human neonates with HCME are not known. A well-validated rabbit model o...

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Autores principales: Warn, Peter A., Livermore, Joanne, Howard, Susan, Felton, Timothy W., Sharp, Andrew, Gregson, Lea, Goodwin, Joanne, Petraitiene, Ruta, Petraitis, Vidmantas, Cohen-Wolkowiez, Michael, Walsh, Thomas J., Benjamin, Daniel K., Hope, William W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264209/
https://ncbi.nlm.nih.gov/pubmed/22123680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05826-11
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