Behavioral Characterization of Knockin Mice with Mutations M287L and Q266I in the Glycine Receptor α1 Subunit

We used behavioral pharmacology to characterize heterozygous knockin mice with mutations (Q266I or M287L) in the α1 subunit of the glycine receptor (GlyR) (J Pharmacol Exp Ther 340:304–316, 2012). These mutations were designed to reduce (M287L) or eliminate (Q266I) ethanol potentiation of GlyR funct...

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Bibliografiska uppgifter
Huvudupphovsmän: Blednov, Yuri A., Benavidez, Jill M., Homanics, Gregg E., Harris, R. Adron
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2012
Ämnen:
Neuropharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263963/
https://ncbi.nlm.nih.gov/pubmed/22037202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.185124
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