Llwytho...

Mutation of a Zinc-Binding Residue in the Glycine Receptor α1 Subunit Changes Ethanol Sensitivity In Vitro and Alcohol Consumption In Vivo

Ethanol is a widely used drug, yet an understanding of its sites and mechanisms of action remains incomplete. Among the protein targets of ethanol are glycine receptors (GlyRs), which are potentiated by millimolar concentrations of ethanol. In addition, zinc ions also modulate GlyR function, and rec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McCracken, Lindsay M., Blednov, Yuri A., Trudell, James R., Benavidez, Jillian M., Betz, Heinrich, Harris, R. Adron
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558822/
https://ncbi.nlm.nih.gov/pubmed/23230213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.197707
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!