Načítá se...

Mutation of a Zinc-Binding Residue in the Glycine Receptor α1 Subunit Changes Ethanol Sensitivity In Vitro and Alcohol Consumption In Vivo

Ethanol is a widely used drug, yet an understanding of its sites and mechanisms of action remains incomplete. Among the protein targets of ethanol are glycine receptors (GlyRs), which are potentiated by millimolar concentrations of ethanol. In addition, zinc ions also modulate GlyR function, and rec...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: McCracken, Lindsay M., Blednov, Yuri A., Trudell, James R., Benavidez, Jillian M., Betz, Heinrich, Harris, R. Adron
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558822/
https://ncbi.nlm.nih.gov/pubmed/23230213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.197707
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!