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Transduction, Tropism, and Biodistribution of AAV Vectors in the Lacrimal Gland

PURPOSE. The lacrimal gland (LG) delivers defensive and metabolic factors to the ocular surface. These functions may be disrupted in several diseases, and for most of them there is no cure. The aim of this study is to investigate conditions and limitations for using adeno-associated virus (AAV) vect...

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Hlavní autoři: Rocha, Eduardo M., Di Pasquale, Giovanni, Riveros, Paola Perez, Quinn, Kathrina, Handelman, Beverly, Chiorini, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Association for Research in Vision and Ophthalmology, Inc. 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263920/
https://ncbi.nlm.nih.gov/pubmed/22110082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8171
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