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Glycated AAV Vectors: Chemical Redirection of Viral Tissue Tropism
A chemical approach for selective masking of arginine residues on viral capsids, featuring an exogenous glycation reaction has been developed. Reaction of adeno-associated viral (AAV) capsids with the α-dicarbonyl compound, methylglyoxal resulted in formation of arginine adducts. Specifically, surfa...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089942/ https://ncbi.nlm.nih.gov/pubmed/21388193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100477g |
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