Regulation of SIRT6 protein levels by nutrient availability

Sirtuins have been shown to regulate life-span in response to nutritional availability. We show here that levels of the mammalian sirtuin, SIRT6, increased upon nutrient deprivation in cultured cells, in mice after fasting, and in rats fed a calorie-restricted diet. The increase in SIRT6 levels is d...

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Autors principals: Kanfi, Yariv, Shalman, Ronnie, Peshti, Victoria, Pilosof, Shmuel N., Gozlan, Yosi M., Pearson, Kevin J., Lerrer, Batya, Moazed, Danesh, Marine, Jean-Christophe, de Cabo, Rafael, Cohen, Haim Y.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263697/
https://ncbi.nlm.nih.gov/pubmed/18242175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.01.019
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