Sirt6 alters adult hippocampal neurogenesis

Sirtuins are pleiotropic NAD(+) dependent histone deacetylases involved in metabolism, DNA damage repair, inflammation and stress resistance. SIRT6, a member of the sirtuin family, regulates the process of normal aging and increases the lifespan of male mice over-expressing Sirt6 by 15%. Neurogenesi...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Okun, Eitan, Marton, Daniel, Cohen, Daniel, Griffioen, Kathleen, Kanfi, Yariv, Illouz, Tomer, Madar, Ravit, Cohen, Haim Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482455/
https://ncbi.nlm.nih.gov/pubmed/28644902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179681
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