Characterization of physiological defects in adult SIRT6(-/-) mice

The NAD+-dependent SIRT6 deacetylase was shown to be a major regulator of lifespan and healthspan. Mice deficient for SIRT6 develop a premature aging phenotype and metabolic defects, and die before four weeks of age. Thus, the effect of SIRT6 deficiency in adult mice is unknown. Here we show that SI...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Peshti, Victoria, Obolensky, Alexey, Nahum, Liat, Kanfi, Yariv, Rathaus, Moran, Avraham, Maytal, Tinman, Simon, Alt, Fredrick W., Banin, Eyal, Cohen, Haim Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407791/
https://ncbi.nlm.nih.gov/pubmed/28448551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176371
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars