Promoter Methylation of RASSF1A Associates to Adult Secondary Glioblastomas and Pediatric Glioblastomas

While allelic losses and mutations of tumor suppressor genes implicated in the etiology of astrocytoma have been widely assessed, the role of epigenetics is still a matter of study. We analyzed the frequency of promoter hypermethylation by methylation-specific PCR (MSP) in five tumor suppressor gene...

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Main Authors: Muñoz, Jorge, Inda, María del Mar, Lázcoz, Paula, Zazpe, Idoya, Fan, Xing, Alfaro, Jorge, Tuñón, Teresa, Rey, Juan A., Castresana, Javier S.
Formato: Artigo
Idioma:Inglês
Publicado: International Scholarly Research Network 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263565/
https://ncbi.nlm.nih.gov/pubmed/22389839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/576578
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