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Promoter Methylation of RASSF1A Associates to Adult Secondary Glioblastomas and Pediatric Glioblastomas

While allelic losses and mutations of tumor suppressor genes implicated in the etiology of astrocytoma have been widely assessed, the role of epigenetics is still a matter of study. We analyzed the frequency of promoter hypermethylation by methylation-specific PCR (MSP) in five tumor suppressor gene...

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Detalhes bibliográficos
Main Authors: Muñoz, Jorge, Inda, María del Mar, Lázcoz, Paula, Zazpe, Idoya, Fan, Xing, Alfaro, Jorge, Tuñón, Teresa, Rey, Juan A., Castresana, Javier S.
Formato: Artigo
Idioma:Inglês
Publicado em: International Scholarly Research Network 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263565/
https://ncbi.nlm.nih.gov/pubmed/22389839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/576578
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