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Synergistic Inhibition of Butyrylcholinesterase by Galantamine and Citalopram
BACKGROUND: Many persons with Alzheimer’s disease (AD) treated with galantamine appear to receive additional cognitive benefit from citalopram. Both drugs inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). These enzymes co-regulate acetylcholine catabolism. In AD brain, AChE is d...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263522/ https://ncbi.nlm.nih.gov/pubmed/21872646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2011.08.010 |
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