Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease

INTRODUCTION: Diagnosis of Alzheimer's disease (AD) in vivo, by molecular imaging of amyloid or tau, is constrained because similar changes can be found in brains of cognitively normal individuals. Butyrylcholinesterase (BChE), which becomes associated with these structures in AD, could elevate...

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Udgivet i:Alzheimers Dement (N Y)
Main Authors: DeBay, Drew R., Reid, George A., Pottie, Ian R., Martin, Earl, Bowen, Chris V., Darvesh, Sultan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651425/
https://ncbi.nlm.nih.gov/pubmed/29067326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2017.01.005
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